The Effect of Mulberry Fruits Consumption on Lipid Profiles in Hypercholesterolemic Subjects: A Randomized Controlled Trial
| Autor: | Tipanee Senawong, Akkarach Bumrungpert, Patcharanee Pavadhgul, Wiroje Kaewruang, Anchalee Sirikanchanarod |
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| Rok vydání: | 2016 |
| Předmět: |
0106 biological sciences
Health (social science) Alternative therapy Medicine (miscellaneous) Low density lipoprotein cholesterol Intervention group Biology 01 natural sciences law.invention chemistry.chemical_compound 0404 agricultural biotechnology Animal science High-density lipoprotein Randomized controlled trial law Botany General Pharmacology Toxicology and Pharmaceutics Nutrition and Dietetics Cholesterol Dietary intake 04 agricultural and veterinary sciences 040401 food science chemistry Anthocyanin lipids (amino acids peptides and proteins) 010606 plant biology & botany |
| Zdroj: | Journal of Pharmacy and Nutrition Sciences. 6:7-14 |
| ISSN: | 1927-5951 2223-3806 |
| DOI: | 10.6000/1927-5951.2016.06.01.2 |
| Popis: | Mulberry (Morus alba) fruit is abundant nutrients and phytochemicals, especially anthocyanins. Mulberries have anti-oxidant and anti-hyperlipidaemic effects both in vitroand animal models. However, the effect of mulberry fruits on lipid profiles in human is unknown. The aim of this study was to determine the effect of mulberry fruit consumption on lipid profiles in hypercholesterolemic subjects. This study is an experimental study, with a randomized controlled trial. Fifty-eight hypercholesterolemic subjects (aged 30-60 years) were recruited. The intervention group received freeze-dried mulberry 45 g (325 mg anthocyanins) per day for six weeks. The control group had their usual dietary intake for the same period of time. After six weeks, mulberry consumption significantly decreased the level of total cholesterol (TC) (- 3.73 % vs. 3.33 %, p < 0.001) and low density lipoprotein cholesterol (LDL-C) (- 6.53 % vs. 0.15 %, p < 0.001) compared to the control group. No change in triacylglycerol (TAG) and high density lipoprotein cholesterol (HDL-C). Mulberry consumption ameliorates TC and LDL-C concentrations. The mulberry fruits may be an alternative therapy for hypercholesterolemia patients and a cardiovascular disease protective for people in general. |
| Databáze: | OpenAIRE |
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