Periodic variations of blood pressure and heart rate in premature neonates
Autor: | R. F. Makhmutov, Kuznetsov AIu, Grebenchikova Oa, Valery Likhvantsev, S. G. Donich, Peretrukin Ai, E. P. Fomchenkov, Shloznikov Bm |
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Rok vydání: | 1990 |
Předmět: | |
Zdroj: | Bulletin of Experimental Biology and Medicine. 109:272-274 |
ISSN: | 1573-8221 0007-4888 |
Popis: | The antinociceptive properties of dalargin (D) under nembutal anesthesia and artificial ventilation were studied in hemodynamic response to mechanical algesic stimulation in rats. D was introduced i/v (20 micrograms/kg) against a background of myoplegia with Arduan (0.1 mg/kg) and without it. The naloxon (100 micrograms/kg) prevented the protective effects of D. It is considered that injection of D (20 micrograms/kg) on the background of total myoplegia and artificial ventilation prevented hemodynamic response on algesic stimulus. Subsequent dose increase of opium peptide up to 3500 micrograms/kg does not cause amplification of protective properties. |
Databáze: | OpenAIRE |
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