Development of a New Practical Synthesis of a 5-HT2C Receptor Agonist

Autor:	Gontcharov Alexander, Bernatchez Michel, Sam Tadayon, Michel Cantin, Gulnaz Khafizova, Qing Yu, Dahui Zhou, Gary Paul Stack, Chia-Cheng Shaw, Lankau Mark, John R. Potoski, Jonathan Laird Gross
Rok vydání:	2010
Předmět:	Agonist chemistry.chemical_compound chemistry Stereochemistry medicine.drug_class Aryl Organic Chemistry medicine Epoxide Glycidyl tosylate 5-HT2C receptor agonist Physical and Theoretical Chemistry Receptor
Zdroj:	Organic Process Research & Development. 14:1438-1447
ISSN:	1520-586X 1083-6160
DOI:	10.1021/op100233f
Popis:	A new practical synthesis of a 5-HT2C receptor agonist has been developed and implemented on multikilogram scale. The key step, the selective epoxide opening in the glycidyl tosylate with the aryl ...
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::60c5e68723695ad0eddc89ef4cd0495c https://doi.org/10.1021/op100233f Zobrazit plný text záznamu