Supplementing Arginine during Sepsis: from Theory to Clinical Practice

Autor: M. J. Bruins, M. Poeze
Rok vydání: 2003
Předmět:
Zdroj: Intensive Care Medicine ISBN: 9781475755503
DOI: 10.1007/978-1-4757-5548-0_10
Popis: Arginine has important roles in the transport, storage, and excretion of nitrogen by disposition of ammonia via the urea cycle. Moreover, arginine is pivotal in metabolic functions since it serves as a precursor of nitric oxide (NO), polyamines, and other molecules. Humans obtain arginine from dietary sources and by endogenous synthesis. In humans, arginine is considered a conditionally essential amino acid since stress conditions with increased arginine demand such as sepsis and inflammation indicate that exogenous arginine is required for a positive nitrogen balance.
Databáze: OpenAIRE