Popis: |
Periungual vitiligo lesions are usually resistant to medical treatment, and their response to surgical management is often disappointing. They are different from non-acral lesions in several aspects, the most important of which is the lack of pilosebaceous follicles, the most important melanocyte reservoirs in vitiligo. This resistance of periungual lesions to therapy should not lead to complete loss of hope in the recovery of those cases. Combining several medical therapies, ablative therapies, and phototherapies or using surgical grafting techniques modified to suit this unique site may improve the outcome of therapy. This chapter focuses on how to manage cases with periungual vitiligo lesions taking into consideration the disease duration, activity, and size of the lesions in order to be able to offer a tailored treatment plan for each patient. |