Association of changes in mental health with weight loss during intensive lifestyle intervention: does the timing matter?

Autor: Stephen M. Schueller, N. Alhalel, M. J. O'Brien
Rok vydání: 2018
Předmět:
Zdroj: Obesity Science & Practice. 4:153-158
ISSN: 2055-2238
DOI: 10.1002/osp4.157
Popis: Author(s): Alhalel, N; Schueller, SM; O'Brien, MJ | Abstract: Objective:This study examined changes in mental health symptoms and weight during weight loss treatment. It was hypothesized that worsening mental health would negatively impact weight loss. Methods:Data were analyzed from a trial of 92 Hispanic women with overweight/obesity and prediabetes, who were randomized to receive intensive lifestyle intervention (ILI), metformin 1,700nmg daily, or standard care. Depression, anxiety and perceived stress were assessed at 0, 6 and 12nmonths. Six- and 12-month weight change was compared among participants whose symptom scores worsened on any mental health measure (W) vs. improved or remained stable on all three (I/S). Results:Among ILI participants, the 12-month difference in weight loss between I/S and W groups was statistically significant: -5.1nkg (Pn=n0.001). From baseline to 6nmonths, ILI participants in I/S and W groups experienced comparable weight loss. However, from 6 to 12nmonths, W participants regained weight, whereas I/S participants experienced continued weight loss. In the metformin and standard care arms, there was no weight difference between I/S and W groups. Conclusions:In ILI, 12-month improvement or stability in mental health was significantly associated with weight loss. Weight trajectories between I/S and W groups diverged at 6nmonths.
Databáze: OpenAIRE
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