Mayaro Virus Infection: Clinical Features and Global Threat
| Autor: | Sérgio Oliveira de Paula, Luciana de Souza Fernandes, Cynthia Canêdo da Silva, Roberto Sousa Dias, Franciele Martins Santos |
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| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
Cultural Studies Linguistics and Language History medicine.medical_specialty business.industry Inflammatory response 030106 microbiology Disease control Language and Linguistics Virus 03 medical and health sciences Health services 0302 clinical medicine Mayaro fever Anthropology Pandemic Epidemiology medicine 030212 general & internal medicine Vector (molecular biology) Intensive care medicine business |
| Zdroj: | Current Treatment Options in Infectious Diseases. 12:387-397 |
| ISSN: | 1534-6250 |
| Popis: | This review aimed to compile the main studies on the Mayaro virus (MAYV), addressing the clinical manifestations of Mayaro fever, in addition to assessing the possibility of epidemic events and a possible pandemic on a global scale. Recent studies using animal models and the evaluation of infection in humans demonstrate that MAYV induces a strong inflammatory response that plays an important role in the development and progression of tissue damage and in the induction of myalgia and arthralgia common to the infection. Due to the similarity of symptoms with other co-circulating arboviruses, differential diagnosis is difficult, which contributes to underestimates of the actual number of cases, effecting epidemiological studies. The development of new methods for molecular diagnosis, faster and more sensitive, is extremely important for overcoming this complication. As there is still no specific treatment or vaccine for MAYV, measures for the prevention and containment of the vector are the best alternatives for disease control. The increase in the number of possible vectors and their geographic distribution require worldwide health services to dedicate more attention to MAYV, especially in countries in tropical and subtropical regions. Its potential expansion in urbanized areas signals an alert for greater efforts to be made in the treatment and control of the virus. |
| Databáze: | OpenAIRE |
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