Macroporous Calcium Phosphate Bioceramics as Drug Release Agents: A Kinetics Study of Ampicillin Release

Autor:	José Sílvio Veras Albuquerque, Giovanilton Ferreira da Silva, Andrea Lopes de Oliveira Ferreira, Ricardo Emílio Ferreira Quevedo Nogueira, I.W.L. Franca
Rok vydání:	2008
Předmět:	Materials science Biocompatibility Mechanical Engineering Kinetics chemistry.chemical_element Bioceramic Calcium Controlled release chemistry Chemical engineering Mechanics of Materials Ampicillin Drug delivery medicine Drug release General Materials Science medicine.drug Biomedical engineering
Zdroj:	Key Engineering Materials. :675-678
ISSN:	1662-9795
DOI:	10.4028/www.scientific.net/kem.396-398.675
Popis:	Semi-synthetic beta-lactam antibiotics are the most important class of antibacterial agents. Their use in veterinary and human medicine is in continuous expansion. Calcium phosphate bioceramics have been used in medicine and dentistry for nearly 30 years. Calcium phosphate ceramics (CPC) are nowadays being widely used as drug delivery systems because of their desirable properties such as biocompatibility, bioresorbability, controlled release etc. In recent years In this work, kinetic models to describe ampicillin adsorption from CPC were investigated. Calcium phosphate bioceramic are analogous to the mineral component of bones, its properties make it suitable for implant materials and delivery agents of drugs
Databáze:	OpenAIRE
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