Alterations of serum high sensitive C reactive protein and lipid levels in newly diagnosed myocardial infarction subjects

Autor: D. Balakrishna, D. Raja Rajeswari, R. R. Aparna, K. Ramalingam, R. Viswa Kumar
Rok vydání: 2019
Předmět:
Zdroj: International Journal of Research in Medical Sciences. 7:4682
ISSN: 2320-6012
2320-6071
DOI: 10.18203/2320-6012.ijrms20195538
Popis: Background: Acute Myocardial Infarction (AMI) is one of the major causes of mortality in the world. Atherosclerosis leading to AMI is the most common and severe clinical manifestation observed. Dyslipidemia is one of main traditional risk factor for MI, but in more than 50% of CHD events dyslipidemia was absent. Atherosclerosis is considered as both a chronic inflammatory condition and a disorder of lipid metabolism. The present study was aimed to estimate the levels of serum lipids (total cholesterol, LDL cholesterol, HDL cholesterol) and hs-CRP an inflammatory marker in newly diagnosed AMI cases and to find out any correlation between these two.Methods: The study was conducted on 50 newly diagnosed myocardial infarction cases, admitted in Cardiology Department Narayana Medical College, Nellore. Both the sexes were included. Fifty age and sex matched healthy individuals were selected as controls. Lipid levels are estimated by end point colorimetric assay (HUMANSTAR kit) and hs-CRP was estimated by immunofluorescence technique (Boditechkit).Results: Significant raised levels of hs-CRP (p value
Databáze: OpenAIRE