Protein-Malnutrition bei pädiatrischen Patienten mit onkologischen Erkrankungen*

Autor: Z. Camaya, Bruckner R, Howanietz H, Pietschnig B, Thun-Hohenstein L, Ferdinand Haschke, Jürgenssen Oa
Rok vydání: 1987
Předmět:
Zdroj: Klinische Pädiatrie. 199:73-76
ISSN: 1439-3824
0300-8630
DOI: 10.1055/s-2008-1026765
Popis: To study the frequency of protein-caloric malnutrition in children (n = 16) with malignant diseases, we measured serum-albumin, -transferrin, -prealbumin and -retinol-binding protein (Radial immunodiffusion) before treatment was started. In 9 children at least 3 of the 4 rapid-turnover proteins were below the age-specific reference values. 7 patients (44%) with low rapid turnover proteins were free from infection, liver and renal dysfunction and thus, diagnosis of protein-caloric malnutrition was established. Anthropometric parameters as weight for age and the weight/height ratio did not predict protein-caloric malnutrition. Nutritional therapy (enteral, parenteral) during a period of 2 weeks resulted in significant increase of albumin (p less than 0.05), prealbumin (p less than 0.01) and retinol-binding protein (p less than 0.01). Rapid turnover proteins can be easily measured in each laboratory and are useful in diagnosis and treatment of protein-caloric malnutrition of children with malignant diseases as long as the limitations of this method are not neglected.
Databáze: OpenAIRE