Protein-Malnutrition bei pädiatrischen Patienten mit onkologischen Erkrankungen*
Autor: | Z. Camaya, Bruckner R, Howanietz H, Pietschnig B, Thun-Hohenstein L, Ferdinand Haschke, Jürgenssen Oa |
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Rok vydání: | 1987 |
Předmět: |
Radial immunodiffusion
chemistry.chemical_classification medicine.medical_specialty biology business.industry Albumin medicine.disease Malnutrition in children Enteral administration Gastroenterology Transthyretin Malnutrition chemistry Transferrin Internal medicine Pediatrics Perinatology and Child Health biology.protein medicine Medical nutrition therapy business |
Zdroj: | Klinische Pädiatrie. 199:73-76 |
ISSN: | 1439-3824 0300-8630 |
DOI: | 10.1055/s-2008-1026765 |
Popis: | To study the frequency of protein-caloric malnutrition in children (n = 16) with malignant diseases, we measured serum-albumin, -transferrin, -prealbumin and -retinol-binding protein (Radial immunodiffusion) before treatment was started. In 9 children at least 3 of the 4 rapid-turnover proteins were below the age-specific reference values. 7 patients (44%) with low rapid turnover proteins were free from infection, liver and renal dysfunction and thus, diagnosis of protein-caloric malnutrition was established. Anthropometric parameters as weight for age and the weight/height ratio did not predict protein-caloric malnutrition. Nutritional therapy (enteral, parenteral) during a period of 2 weeks resulted in significant increase of albumin (p less than 0.05), prealbumin (p less than 0.01) and retinol-binding protein (p less than 0.01). Rapid turnover proteins can be easily measured in each laboratory and are useful in diagnosis and treatment of protein-caloric malnutrition of children with malignant diseases as long as the limitations of this method are not neglected. |
Databáze: | OpenAIRE |
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