Value of Combination of the A2DS2 Score and IL-6 in Predicting Stroke-Associated Pneumonia
| Autor: | Yonghong Dai, Zuowen Zhang, Yue Chen, Jun Jun Yang |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Multivariate analysis Receiver operating characteristic business.industry Atrial fibrillation Retrospective cohort study Odds ratio Stepwise regression medicine.disease Gastroenterology Confidence interval 030227 psychiatry 03 medical and health sciences 0302 clinical medicine Internal medicine medicine business Stroke 030217 neurology & neurosurgery |
| Zdroj: | Neuropsychiatric Disease and Treatment. 16:2353-2359 |
| ISSN: | 1178-2021 |
| Popis: | Purpose To evaluate the value of the combination of the age, atrial fibrillation, dysphagia, male sex, and National Institutes of Health Stroke Scale (A2DS2) score and serum interleukin 6 (IL-6) concentration in predicting stroke-associated pneumonia (SAP). Patients and Methods A total of 398 patients with acute ischemic stroke (AIS) from the medical ward was included in this retrospective study. They were divided into the SAP group and non-SAP group according to the diagnostic criteria of SAP. Multivariate analysis was performed to analyze the association between the A2DS2 score, serum IL-6 concentration, and SAP using a backward stepwise logistic regression model. The receiver operating characteristic (ROC) curve was used to evaluate the value of the A2DS2 score, serum IL-6 concentration and combination of A2DS2 score and IL-6 in predicting SAP. Results SAP was diagnosed in 70 patients (17.6%). Multivariate analysis showed that the A2DS2 score (odds ratio [OR]: 2.25, 95% confidence interval [CI]: 1.17–4.99, P=0.017) and serum IL-6 concentration (OR: 1.76, 95% CI: 1.44–1.95, P |
| Databáze: | OpenAIRE |
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