Reaction of secondary N-1-(2-chloroalkylidene)amines with lithium tetrahydridoaluminate: Synthesis and rearrangement of 1,2,2-trisubstituted aziridines

Autor:	Norbert De Kimpe, Laurent De Buyck, Niceas Schamp, Roland Verhé
Rok vydání:	2010
Předmět:	chemistry.chemical_compound Reaction mechanism chemistry chemistry.chemical_element Organic chemistry Lithium General Chemistry Lithium aluminium hydride
Zdroj:	Recueil des Travaux Chimiques des Pays-Bas. 96:242-246
ISSN:	0165-0513
Popis:	1,2,2-Trisubstituted aziridines have been prepared by reduction of secondary N-1-(2-chloroalkylidene)amines with lithium aluminium hydride. N-Substituted 1-azaspiro[2.5]octanes (spiroaziridines) have been synthesized by this method. Under appropriate gas chromatographic conditions, 1,2,2-trisubstituted aziridines underwent rearrangement to the corresponding secondary N-1-(alkylidene)amines. The reaction mechanisms are discussed.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::6053dfb31c189b128aa65a9138d45334 https://doi.org/10.1002/recl.19770960908 Zobrazit plný text záznamu