International Multicenter Term PROM Study: Evaluation of predictors of neonatal infection in infants born to patients with premature rupture of membranes at term

Autor: Arne Ohlsson, Mary E. Hannah, Dan Farine, Julie Weston, E. Wang, Gonen Ohel, P. Gareth R. Seaward, K. Haque, Terri L. Myhr, Ellen Hodnett
Rok vydání: 1998
Předmět:
Zdroj: American Journal of Obstetrics and Gynecology. 179:635-639
ISSN: 0002-9378
DOI: 10.1016/s0002-9378(98)70056-0
Popis: Objective Our objective was to determine significant predictors for the development of neonatal infection in infants born to patients with premature rupture of membranes at term. Study design Multivariate analysis was used to determine the significant predictors of neonatal infection in infants born to women with premature rupture of the membranes who were enrolled in the Term PROM Study. In a randomized, controlled trial, the Term PROM Study recently compared induction of labor with expectant management for premature rupture of membranes at term. Results The following variables were identified as independent predictors of neonatal infection: clinical chorioamnionitis (odds ratio 5.89, P or = 48 hours from membrane rupture to active labor (vs Conclusions Among infants born to patients with premature rupture of membranes at term, clinical chorioamnionitis and maternal colonization with group B streptococci are the most important predictors of subsequent neonatal infection.
Databáze: OpenAIRE