Purification and Production of Novel Angiotensin I-Converting Enzyme (ACE) Inhibitory Bioactive Peptides Derived from Fermented Goat Milk
| Autor: | Gauravkumar Panchal, Subrota Hati, Amar Sakure, Heena Parmar |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
chemistry.chemical_classification
biology 010405 organic chemistry Chemistry PH reduction food and beverages Bioengineering Angiotensin-converting enzyme Titratable acid biology.organism_classification 01 natural sciences Biochemistry Aminopeptidase 0104 chemical sciences Analytical Chemistry Amino acid Lactobacillus Drug Discovery biology.protein Molecular Medicine Fermentation Food science Incubation |
| Zdroj: | International Journal of Peptide Research and Therapeutics. 26:997-1011 |
| ISSN: | 1573-3904 1573-3149 |
| DOI: | 10.1007/s10989-019-09902-7 |
| Popis: | In the study, five different Lactobacillus cultures i.e. L. rhamnosus (NK2) (KR080695), L. casei (NK9) (KR732325), L. fermentum (M5) (KU366365), L. paracasei (M16) (KU366368), L. fermentum TDS030603 (MTCC 25067) (LF) were studied for their growth behavior, PepX and ACE-inhibitory activities and peptides production from fermented goat milk (Capra aegagrus hircus). The acidity, pH and lactic counts were evaluated for 0, 6, 12, 24 and 48 h at 37 °C. During their growth in heat treated goat milk (90 °C for 10-15 min), M5 significantly showed maximum titratable acidity (3.25%LA) and highest pH reduction (pH 3.10), while M16 exhibited highest lactic counts (9.35 log cfu/ml) up to 12 h of incubation (P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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