Autor: |
D V Dapper, Beatrice Olatundun Oluwatayo, E B Umoren, O. N. Ilochi, T. A. Kolawole |
Rok vydání: |
2020 |
Předmět: |
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Zdroj: |
Journal of Advances in Medical and Pharmaceutical Sciences. :22-35 |
ISSN: |
2394-1111 |
DOI: |
10.9734/jamps/2020/v22i1230208 |
Popis: |
Introduction: Lead (Pb) is a transition metal and a known male reproductive toxicant that induces its effects mainly through oxidative stress. This study investigated the effects of L-Citrulline (Cit) supplement on reproductive functions and antioxidant activities in Lead acetate treated male rats. Materials and Methods: Twenty male rats (180-200 g) were grouped into four and treated as follows; Group 1 (Control), given distilled water, Group 2 was given Pb acetate (2.25mg/kg), Group 3 was co-treated with Pb acetate (2.25mg/kg) and Cit (900mg/kg) and Group 4 was given Cit (900mg/kg) only. All administrations were done orally for thirty days. Caudal sperm, serum hormone levels and testicular antioxidant activities and Nitric oxide levels were evaluated at the end administrations. Results: Results showed decrease (p |
Databáze: |
OpenAIRE |
Externí odkaz: |
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