Access to chiral cyano-containing five-membered rings through enantioconvergent rhodium-catalyzed cascade cyclization of a diastereoisomeric E/Z mixture of 1,6-enynes

Autor:	Sylvain Darses, Aymane Selmani
Rok vydání:	2019
Předmět:	010405 organic chemistry Chemistry Organic Chemistry Intermolecular force chemistry.chemical_element 010402 general chemistry 01 natural sciences Medicinal chemistry 0104 chemical sciences Rhodium Catalysis Cascade Reagent Enantiomer
Zdroj:	Organic Chemistry Frontiers. 6:3978-3982
ISSN:	2052-4129
Popis:	In contrast to the intermolecular rhodium-catalyzed asymmetric 1,4-addition of organometallic reagents to activated alkenes, the asymmetric arylative cyclization of a diastereoisomeric E/Z mixture of 1,6-enynes afforded only one major enantiomer.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::602dadc8afcc1dde075cdbf3d2740ea0 https://doi.org/10.1039/c9qo01264h Zobrazit plný text záznamu