Die computertomographisch geleitete stereotaktische interstitielle Therapie von Hirntumoren mittels temporärer oder permanenter Implantation von125Jod-Seeds

Autor: Thiel Hj, Sauer R, Müller Rg, Huk Wj
Rok vydání: 1983
Předmět:
Zdroj: RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren. 138:348-355
ISSN: 1438-9010
1438-9029
DOI: 10.1055/s-2008-1055736
Popis: Therapy resistance of inoperable malignant gliomas is an unsolved problem for radiotherapy. A combination of interstitial therapy and percutaneous high voltage therapy is described which should improve the prognosis of brain tumours when it has been perfected. For all tumours of low malignancy we recommend the permanent implantation of 125iodine seeds of low activity (10-60 mCi 125I, DO = 6-10 rad/h.) as the primary form of treatment, possibly supplemented by high voltage therapy. For tumours of higher malignancy, temporary implantation of high activity 125I is indicated (more than 200 mCi, DO = 25-100 rad/h.) as local boost before or after total volume irradiation of brain. Our experience of 30 patients up to date is encouraging.
Databáze: OpenAIRE