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Background Sarcopenia is the loss of skeletal muscle mass, strength and function that occurs as a consequence of aging. This condition result in physical disability, which limits the capacity to walk, increases the risk of falls and osteoporotic fractures. Several studies suggested an inverse relation between 25OHD serum levels, muscular strength and physical performance in the eldest. Objectives To evaluate if vitamin D supplementation in patients > 50 years improves muscle mass, strength and performance in older patients. Methods We performed a systematic review through Medline, Cochrane Library, and EMBASE. Inclusion criteria: 1) patients > 50 years old, 2) receiving treatment with vitamin D 3) muscle mass and muscle strength measurements 4) systematic reviews (SR) 5) randomized clinical trials (RCT) 6) Papers written in English or Spanish. Results Five studies were included (4 SR and 1 RCT), n patients ranged from 121 to 5615. Patients mean age oscillated between 58-88 years, receiving variable vitamin D dose. Follow-up period fluctuated from 6 to 12 months. Conclusion · Vitamin D supplementation in patients > 65 years with inadequate 25OHD serum levels, improve muscular strength. · There were no benefits in muscle mass or muscular performance. References [1] Beaudart C, Dawson A, Shaw S C, Harvey N H, Kanjis J A, Binkley N, et al. Nutrition and Physical activity in the prevention and treatment of sarcopenia.: systematic review. Osteopor Int2017; 28: 1817-1833. [2] Cangussu LM, Nahas-Neto J, Orsatti CL, Bueloni-Dias FN, Nahas EAP. Effect of Vitamin D supplementation alone on muscle function in postmenopausal women: a randomized double-blind, placebo-controlled clinical trial. Osteopor Int 2015; 26:2413-2421. Disclosure of Interests None declared |
