Enantioselective synthesis of (-)-physostigmine

Autor:	M. Hirama, Seiichi Takano, Emiko Goto, Kunio Ogasawara
Rok vydání:	1982
Předmět:	Physostigmine biology Chemistry Stereochemistry Alkaloid Synthon Enantioselective synthesis Ether General Chemistry General Medicine biology.organism_classification Physostigma venenosum chemistry.chemical_compound Eseroline Esermethole Drug Discovery medicine Organic chemistry medicine.drug
Zdroj:	Chemical and Pharmaceutical Bulletin. 30:2641-2643
ISSN:	1347-5223 0009-2363
Popis:	The first enantioselective synthesis of (-)-physostigmine (1), a potent cholinesterase-inhibiting alkaloid from Physostigma venenosum Balf., has been accomplished using (S)-(-)-benzyl 2, 3-epoxypropyl ether (5) as a chiral synthon.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::6000c3ff630db935ea0603d1b7e9574d https://doi.org/10.1248/cpb.30.2641 Zobrazit plný text záznamu