Diffuse (Generalized) Plane Xanthoma Misdiagnosed as Carotenoderma: Usefulness of Reflectance Confocal Microscopy
| Autor: | Donatella Brancorsini, Viviana Lora, Giovanni Pellacani, Carlo Cota |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Reflectance confocal microscopy
Pathology medicine.medical_specialty business.industry Carotenoderma Generalized plane xanthoma Context (language use) Dermatology General Medicine Pathology and Forensic Medicine 030207 dermatology & venereal diseases 03 medical and health sciences Monoclonal gammopathy 0302 clinical medicine Biopsy Site medicine medicine.symptom business Plane xanthoma Histological examination |
| Zdroj: | The American Journal of Dermatopathology. 42:e167-e169 |
| ISSN: | 0193-1091 |
| Popis: | Diffuse (generalized) plane xanthoma is a rare normolipemic xanthomatosis, frequently associated with multiple myeloma and monoclonal gammopathy. Its clinical presentation is well described, and in most cases, clinical suspicion is immediate. Rarely, it can clinically present with a diffuse and uniform yellowish discoloration, and in this context, several investigations are required to identify the correct diagnosis. We describe a case characterized by progressive diffuse yellow-orange discoloration lasting about 3 years and classified as carotenoderma in which reflectance confocal microscopy addressed the diagnosis and drove the correct selection of the biopsy site. Definitive diagnosis of diffuse (generalized) plane xanthoma was confirmed later by histological examination. |
| Databáze: | OpenAIRE |
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