| Autor: |
Keith F. Chater, Paul Dyson, Andrew Hesketh, Colin P. Smith, Bertolt Gust, Paul Herron, Kay Fowler, Vassilios Mersinias, Tobias Kieser, Graham Hotchkiss, Giselda Bucca |
| Rok vydání: |
2002 |
| Předmět: |
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| DOI: |
10.1016/s0580-9517(02)33018-6 |
| Popis: |
The huge genome (8.7 Mb) and developmental complexity of Streptomyces coelicolor A3(2) present significant challenges for functional genomics. Nevertheless, effective microarrays of PCR-generated gene fragments have been generated in two laboratories, and significant information is accruing from proteome analysis. Genomewide transposon mutagenesis and highly efficient PCR-targeted gene disruption are making genetic intervention straightforward. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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