Strychnine-8-ammonio-2-naphthalenesulfonate-water (1/1/3.5): The first structure of a strychnine or brucine compound with a zwitterionic species

Autor:	Graham Smith, Urs D. Wermuth, David J. Young, Peter Conrad Healy
Rok vydání:	2006
Předmět:	chemistry.chemical_compound Crystallography Brucine chemistry Hydrogen bond Orthorhombic crystal system General Chemistry Strychnine Crystal structure Condensed Matter Physics Hydrate Organometallic chemistry Adduct
Zdroj:	Journal of Chemical Crystallography. 36:805-811
ISSN:	1572-8854 1074-1542
Popis:	The crystal structure of the 1:1 adduct hydrate of strychnine with 1,7-Cleve's acid (8-amino-2-naphthalenesulfonic acid), namely strychnine-8-ammonio-2-naphthalenesulfonate-water (1/1/3.5) has been determined and provides a unique example of a neutral association involving strychnine and an achiral zwitterionic acid species, previously unobserved in the structures of either strychnine or brucine addition compounds. Crystals are orthorhombic, space group P212121, with Z=4 in a cell with dimensions a=10.4484(8), b=30.850(3), c=9.4998(11) A. Hydrogen bonding involving all available proton-donor and acceptor sites on all species gives rise to a three-dimensional framework polymer structure. The crystallographic literature for strychnine and brucine and their compounds is also reviewed.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::5fdd889a945eead9bda7dc5f4f2849c6 https://doi.org/10.1007/s10870-006-9085-5 Zobrazit plný text záznamu Full text from SpringerLink