Efficient synthesis of novel quinazoline-4(1H)-one derivatives by N-halosulfonamides

Autor: Jafar Mahmoudi, Ramin Ghorbani-Vaghei, Azadeh Shahriari, Yaser Maghbooli
Rok vydání: 2016
Předmět:
Zdroj: Research on Chemical Intermediates. 43:983-993
ISSN: 1568-5675
0922-6168
DOI: 10.1007/s11164-016-2678-5
Popis: In this research, a facile, effective and one-pot synthesis of new quinazoline-4(1H)-one derivatives is reported. Isatoic anhydride, acid hydrazides or ammonium acetate and aromatic aldehydes in the presence of N-halosulfonamides; N,N,N′,N′-tetrabromobenzene-1,3-disulfonamide and poly(N-bromo-N-ethylbenzene-1,3-disulfonamide) are used to produce the above-mentioned compounds. In addition, the reaction medium is in agreement with green chemistry principles.
Databáze: OpenAIRE