Primary T-Cell–Rich B-Cell Lymphoma of the Ethmoid Sinus

Autor: Rinaldo F. Canalis, Jun Wang, Sanford M. Weinstein, Nora C. J. Sun
Rok vydání: 2000
Předmět:
Zdroj: Archives of Pathology & Laboratory Medicine. 124:1213-1216
ISSN: 1543-2165
0003-9985
DOI: 10.5858/2000-124-1213-ptcrbc
Popis: T-cell–rich B-cell lymphoma (TCRBCL) is an uncommon and recently recognized variant of B-cell non-Hodgkin lymphoma characterized by a few large neoplastic B cells amid a predominant population of reactive T lymphocytes and variable numbers of histiocytes. Morphologically, TCRBCL resembles a variety of non-Hodgkin lymphomas and Hodgkin disease. Accurate diagnosis and proper treatment are essential to assure a favorable prognosis. To our knowledge, this is the first report of ethmoid sinus presentation of TCRBCL in an Epstein-Barr virus–negative 51-year-old man. Combined chemotherapy and radiotherapy were administered based on the correct diagnosis. The patient has had a complete response with no recurrence during the 5-year follow-up.
Databáze: OpenAIRE