A selective catalytic side chain oxidation of lysine and ornithine derivatives

Autor:	Denys Baskakov, Kai Rossen, Andrej Kolarovič, Michael Kiesel
Rok vydání:	2004
Předmět:	chemistry.chemical_classification Organic Chemistry Lysine chemistry.chemical_element Ornithine Biochemistry Aldehyde Medicinal chemistry Catalysis chemistry.chemical_compound chemistry Oxidation state Peracetic acid Drug Discovery Side chain Organic chemistry Carbon
Zdroj:	Tetrahedron Letters. 45:3023-3025
ISSN:	0040-4039
DOI:	10.1016/j.tetlet.2004.02.115
Popis:	The fully protected derivatives of the diamino acids lysine and ornithine ( n =1, 2) can be oxidized selectively in the side chain using a Mn(OAc) 2 /peracetic acid/NaOAc system. The e or γ carbon, respectively, is converted to the aldehyde oxidation state, protected as the cyclic N , N -acetal.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::5fc3adc886037eada92c1b7ceb716e1b https://doi.org/10.1016/j.tetlet.2004.02.115 Zobrazit plný text záznamu Full Text from ScienceDirect