Cationic ruthenium complex of the formula [RuCl(2,6-diacetylpyridine)(PPh3)2]BArF and its catalytic activity in the formation of enol esters

Autor:	Matthew J. Stark, Nigam P. Rath, Eike B. Bauer, Douglas T. Tang
Rok vydání:	2018
Předmět:	010405 organic chemistry Chemistry Ligand Organic Chemistry Markovnikov's rule Cationic polymerization chemistry.chemical_element 010402 general chemistry 01 natural sciences Biochemistry Medicinal chemistry Enol 0104 chemical sciences Catalysis Ruthenium chemistry.chemical_compound Drug Discovery
Zdroj:	Tetrahedron Letters. 59:873-877
ISSN:	0040-4039
DOI:	10.1016/j.tetlet.2018.01.029
Popis:	A new ruthenium 2,6-diacetylpyridine complex was synthesized and applied in the atom-economic synthesis of enol esters through Markovnikov-directed addition of carboxylic acids to terminal alkynes. The ruthenium complex [RuCl(dap)(PPh3)2]+BArF− was synthesized from [RuCl2(PPh3)2] and the corresponding ligand 2,6-diacetylpyridine (dap). The complex was characterized structurally. The new ruthenium complex was utilized under ambient conditions as a catalyst in the Markovnikov addition of carboxylic acids to terminal alkynes to afford the corresponding enol esters in 93% to 52% isolated yields (85 °C, 16 h reaction time, 1 mol% catalyst loading).
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::5fb6ff4df46233705b9f27198a707497 https://doi.org/10.1016/j.tetlet.2018.01.029 Zobrazit plný text záznamu Full Text from ScienceDirect