Medicinal chemistry approaches to target the MNK–eIF4E axis in cancer
| Autor: | Ann Fernandez, Paige J. Monsen, Leonidas C. Platanias, Gary E. Schiltz |
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| Rok vydání: | 2023 |
| Předmět: | |
| Zdroj: | RSC Medicinal Chemistry. |
| ISSN: | 2632-8682 |
| Popis: | Cap-dependent translation can become defective and lead to aberrant oncogenic translation and uncontrolled proliferation. We discuss the functions of MNK and eIF4E and recent medicinal chemistry to develop small molecules to target this axis. |
| Databáze: | OpenAIRE |
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