Sch 65676: A novel fungal metabolite with the inhibitory activity against the cytomegalovirus protease

Autor:	Arthur King, Min Chu, John Pichardo, Bimal Dasmahapatra, Imbi Truumees, Andrea Hart, Ronald Mierzwa, Mahesh Patel, Mohindar S. Puar, Pradip R. Das
Rok vydání:	1996
Předmět:	Protease Chemistry Stereochemistry medicine.medical_treatment Organic Chemistry Congenital cytomegalovirus infection Secondary metabolite Inhibitory postsynaptic potential medicine.disease Biochemistry Fungal metabolite Drug Discovery medicine Fermentation broth medicine.drug
Zdroj:	Tetrahedron Letters. 37:3943-3946
ISSN:	0040-4039
DOI:	10.1016/0040-4039(96)00748-4
Popis:	A new secondary metabolite, Sch 65676 (1), was isolated from the fermentation broth of a fungal culture. The structure of 1 was elucidated based on comprehensive NMR studies including COSY, NOE and HMBC experiments. Compound 1 displays inhibitory activity against the cytomegalovirus (CMV) protease.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::5f82a906785977255a10ffba9db9b891 https://doi.org/10.1016/0040-4039(96)00748-4 Zobrazit plný text záznamu Full Text from ScienceDirect