A New Tyramine Derivative from the Branches and Leaves of Glycosmis craibii

Autor:	Zhong-Liu Zhou, Qi Zhou, Shou-Yuan Wu, Ziming Chen, Chun-Xiao Jiang, Li-Ping Huang, Guo-Ling Huang
Rok vydání:	2021
Předmět:	biology Stereochemistry Ether Plant Science General Chemistry Tyramine biology.organism_classification General Biochemistry Genetics and Molecular Biology chemistry.chemical_compound chemistry Amide Aurantiamide acetate Glycosmis Two-dimensional nuclear magnetic resonance spectroscopy Human cancer Derivative (chemistry)
Zdroj:	Chemistry of Natural Compounds. 57:894-898
ISSN:	1573-8388 0009-3130
DOI:	10.1007/s10600-021-03505-9
Popis:	A new tyramine derivative, glycosamide A (1), together with two known amide alkaloids, N-benzoyltyramine methyl ether (2) and aurantiamide acetate (3), was isolated from the branches and leaves of Glycosmis craibii Tanaka. Their structures were elucidated through extensive 1D and 2D NMR and HR-ESI-MS spectroscopic analyses. All known compounds were isolated from the genus Glycosmis for the first time. Furthermore, the antiproliferative activities of all isolated alkaloids in vitro were evaluated. Compound 2 displayed weak antiproliferative activities against five human cancer cell lines, HL-60, SMMC-7721, A-549, MCF-7, and SW480.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::5f808e800620c9f369a4499aa4499ecc https://doi.org/10.1007/s10600-021-03505-9 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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