SU-GG-T-570: Selection of CT Image Sets for Treatment Planning in Stereotactic Body Radiation Therapy of Lung Cancer
| Autor: | A. Srisuthep, C. Betzing, T He, Martin Fuss, J Wu |
|---|---|
| Rok vydání: | 2010 |
| Předmět: |
medicine.medical_specialty
business.industry Stereotactic body radiation therapy medicine.medical_treatment Planning target volume General Medicine medicine.disease Radiation therapy Medical imaging Medicine Dosimetry Radiology business Nuclear medicine Radiation treatment planning Lung cancer Free breathing |
| Zdroj: | Medical Physics. 37:3318-3318 |
| ISSN: | 0094-2405 |
| DOI: | 10.1118/1.3468968 |
| Popis: | Purpose: This study investigated the impact on tumordose coverage of treatment plans performed on various CTimage sets in stereotactic body radiation therapy(SBRT) of lungcancer.Methods and Materials: Five patients underwent SBRT for lungcancers were retrospectively investigated. For each patient, a free breathing (FB) CT and a four‐dimensional (4D) CT were acquired. Based on the 4DCT scans, two post‐processing CTimages were reconstructed: average intensity projection CT (AIP) and a low pitch, slow‐scan CT (SCT). The gross target volumes (GTVs) were delineated on the 4DCT images and combined to create the internal target volume (ITV). The planning target volume (PTV) was created by adding a 5 mm margin to the ITV. Treatment plans were performed on the FB CT, ATP CT, and SCT. Plan quality was evaluated by calculating and comparing the 4D dose for each plan using deformable‐image registration. Results: No matter which CTimage sets were used in treatment planning,lungtumors always receive at least the prescribed dose. The average difference in tumor D100 (minimum dose received by 100% of the tumor) is 0.28±0.61Gy (p=0.363) between the plans performed on AIP CT and those on FB CT, 0.62±1.35Gy (p=0.379) between the plans performed on AIP CT and those on SCT, and 0.34±0.77Gy (p=0.379) between the plans performed on FB CT and those on SCT. As for the mean lungdose, the average difference is −0.07±0.15Gy (p=0.390), 0.07±0.11Gy (p=0.221), and 0.14±0.15Gy (p=0.107) respectively. For the total lung V20, the average difference is −0.19±0.26% (p=0.186), 0.13±0.25% (p=0.321), and 0.31±0.27% (p=0.06) respectively. Conclusions: The differences in tumor and lungdose coverage for treatment plans performed on ATP CT, FB CT and SCT are indistinguishable. Those three CTdata sets are equally well in term of dose coverage for treatment planning in lungSBRT. |
| Databáze: | OpenAIRE |
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