Genome Assessment of Antibiotic Resistance Genes in Probiotic Bacteria and a Literature Review

Autor: Sara Naseri, Mehdi Fatahi-Bafghi, Ali Alizehi
Rok vydání: 2021
Předmět:
DOI: 10.21203/rs.3.rs-254514/v1
Popis: Having various clinical applications, probiotic bacteria are currently used in the diet. There are reports of antibiotic resistance genes (ARGs) in these bacteria that can be transferred to other microflora and pathogenic bacteria. The aim of the study is to examine whole-genome sequence analysis in bacteria with probiotic properties. Moreover, this study follows existing issues about the importance and presence of ARGs in these bacteria the dangers of which may affect human health in the years to come. In the present study, 126 complete probiotic bacterial genomes were collected and analysed for ARGs. The results of the study shows there are various antibiotic resistant genes of in these bacteria some of which can be transmitted to other bacteria. We propose microorganisms be applied as a probiotic element in various types of products, antibiogram be conducted for a large number of antibiotics and analysis of complete genome sequence for ARGs prediction.
Databáze: OpenAIRE