Prevalence and Incidence of Systemic Lupus Erythematosus in a Population-Based Registry of American Indian and Alaska Native People, 2007-2009

Autor: Lisa Sumner, Charles G. Helmick, S. Sam Lim, James O. Posever, Elizabeth D. Ferucci, Caroline Gordon, Tammy L. Choromanski, Jasmine R. Gaddy, Janet M. Johnston
Rok vydání: 2014
Předmět:
Zdroj: Arthritis & Rheumatology. 66:2494-2502
ISSN: 2326-5191
DOI: 10.1002/art.38720
Popis: Systemic lupus erythematosus (SLE) is an autoimmune disease with many potential manifestations and complex classification criteria. Estimates of the overall prevalence of SLE in the US have ranged from 15 to 144 per 100,000 (1,2), and the incidence has ranged from 1.8 to 23.2 cases per 100,000 per year (1). Many epidemiologic studies have documented that SLE is more common in women and in racial/ethnic minority populations, especially blacks (1-5). However, studies of the prevalence and incidence of SLE have been limited by difficulty validating the classification criteria for SLE at a population level without detailed medical record review. Furthermore, most studies have focused on white and black populations. Few epidemiologic studies have focused on the prevalence and incidence of SLE in other racial/ethnic minority populations. The prevalence and incidence of SLE in American Indian/Alaska Native populations have been estimated in several studies (6,7). In 2 regional studies in the US American Indian/Alaska Native and Canadian Aboriginal populations (8,9), the age-adjusted prevalence ranged from 42 to 112 per 100,000. In both studies, the prevalence of SLE in these populations was significantly higher than that in the general population. In addition, the Canadian study showed that SLE was more severe in Aboriginal patients and was associated with greater mortality (9). A more recent Canadian study using administrative data revealed an increased prevalence of SLE that was most pronounced in First Nations women older than age 45 years (10). Incidence estimates in the American Indian/Alaska Native population have varied, but a study using Indian Health Service (IHS) hospital discharge records without case validation showed that the mean annual incidence ranged from 1.2 to 4.1 per 100,000 person-years in the 1970s and 1980s, with variation by region (7). In partnership with the Centers for Disease Control and Prevention (CDC), we developed the IHS lupus registry. This registry and 4 other CDC-funded registries were designed to address the limitations of data on the prevalence and incidence of SLE in racial/ethnic minority populations in the US (3). The objective of this population-based registry was to determine the prevalence (in 2007) and average annual incidence (from 2007 to 2009) of SLE in the IHS active clinical population in 3 regions of the US.
Databáze: OpenAIRE
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