| Autor: |
Pei Liu, Xing Quan, Fangyu Wei, Xianjun Deng, Jie Shen, Jiansong Cheng |
| Rok vydání: |
2023 |
| DOI: |
10.22541/au.168277354.48161521/v1 |
| Popis: |
Besides serving as therapeutic agents and building blocks for glycoprotein synthesis, homogeneous synthetic glycopeptides also benefit understanding function of specific glycoform. However, the selectivity coupling of oligosaccharides to a given peptide remains challenging despite the fact that the synthesis of structure-defined complex oligosaccharides has been greatly facilitated by chemoenzymatic based approaches. Herein, a Ca-promoted glycosylation approach was developed to exclusively modify phenolic peptide using a panel of biologically important glycans. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
