| Autor: |
Hartl, Christina, Bertschi, Adrian, Puerto, Regina, Andresen, Carolin, Cheney, Emily, Mittendorf, Elizabeth, Guerriero, Jennifer, Goldberg, Michael |
| Rok vydání: |
2019 |
| DOI: |
10.6084/m9.figshare.9178676.v1 |
| Popis: |
Figure S2. Functional enrichment analysis of unsorted cells highlights the importance of the innate immune system. Mice were inoculated with ID8-Vegf-Defb29 cancer cells. Eight days later, mice were injected with either vehicle or paclitaxel and carboplatin (Chemo). Two days thereafter, peritoneal cells were recovered and assessed by gene expression analysis. (a) The top 84 significantly upregulated genes after chemotherapy treatment with a fold change â Ľ1 were queried for their pathway interactions using the ToppGene Suite gene list enrichment analysis tool. (b) The genes induced by chemotherapy had a significant correlation with myeloid cell populations. (PDF 1020 kb) |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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