Indole derivatives for cyanide detection based on nucleophilic addition and hydrogen-bond interaction
| Autor: | Yilin Zhu, Duxia Cao, Zhiqiang Liu, Ruifang Guan, Miaomiao Xing, Xueying Yu, Muhan Liang, Kangnan Wang, Yatong Sun |
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| Rok vydání: | 2018 |
| Předmět: |
Indole test
Nucleophilic addition Absorption spectroscopy 010405 organic chemistry Chemistry Hydrogen bond Cyanide Organic Chemistry Conjugated system 010402 general chemistry Photochemistry 01 natural sciences Fluorescence 0104 chemical sciences Analytical Chemistry Inorganic Chemistry chemistry.chemical_compound Proton NMR Spectroscopy |
| Zdroj: | Journal of Molecular Structure. 1173:647-652 |
| ISSN: | 0022-2860 |
| Popis: | Two indole organic salt derivatives 1 and 2 with two potential reactive sites for cyanide were synthesized by very simple method. The compounds exhibit highly sensitive and selective response for cyanide with obvious UV–vis absorption, color change and fluorescence quench. Color change under natural and UV light can be observed easily by naked eyes. Their absorption responses for cyanide are markedly different from the corresponding normal cyanide chemosensors because of N H*CN− intermolecular hydrogen-bond interaction. The difference of absorption spectra between these compounds and the corresponding normal cyanide chemosensors were compared. Their recognition mechanisms for cyanide anions were analyzed by in situ 1H NMR and Job's plots. The analysis indicates that cyanide anions are bonded to C C bonds in conjugated bridge of the compounds. At the same time, N H*CN− intermolecular hydrogen-bond interaction is accompanied. These chemosensors have been successfully applied for determination of CN− in living cells. |
| Databáze: | OpenAIRE |
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