Hyalinizing clear cell carcinoma of the parotid gland: Report of a recurrent case with aggressive cytomorphology and behavior diagnosed on fine-needle cytology sample
| Autor: | Francesco Perri, M.I.A.C. Franco Fulciniti M.D., Gerardo Botti, Corrado Aversa, Franco Ionna, Rossella De Cecio, Ettore Pavone, B D Maria Pia Curcio, B D Giuseppina Liguori, B D Anna Cipolletta Campanile, B D Gabriella Aquino, Francesco Caponigro |
|---|---|
| Rok vydání: | 2013 |
| Předmět: |
Pathology
medicine.medical_specialty Histology business.industry Cytology sample Soft tissue Diff-Quik General Medicine medicine.disease Pathology and Forensic Medicine Parotid gland medicine.anatomical_structure Superficial Parotidectomy Cytology medicine Differential diagnosis Hyalinizing clear cell carcinoma business |
| Zdroj: | Diagnostic Cytopathology. 42:63-68 |
| ISSN: | 8755-1039 |
| DOI: | 10.1002/dc.22956 |
| Popis: | A case of recurrent hyalinizing clear cell carcinoma (HCCC) of the parotid gland in a 46-year-old female is here introduced. The patient had undergone a left superficial parotidectomy 6 months ago in another institution for an alleged benign, circumscribed mass 2.4 cm in diameter of the left parotid gland. Histopathological examination revealed a poorly differentiated HCCC bearing a EWSR-1 translocation on FISH examination. Fine Needle Cytology (FNC) was performed on three separate soft tissue masses in the pre-masseterine area and a cytological diagnosis of recurrent, poorly differentiated, possibly aggressive variant of HCCC, was rendered. FISH performed on a destained Diff Quik stained smear demonstrated an ESWR-1 translocation, which supported the cytopathological diagnosis. The cytomorphologic features and the differential diagnosis of this aggressive variant of HCCC are briefly discussed. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text