Quantitative T1 mapping and absolute water content measurement using MRI
| Autor: | Heiko Neeb, Thomas Dierkes, N. Jon Shah |
|---|---|
| Rok vydání: | 2004 |
| Předmět: |
Systematic error
medicine.diagnostic_test biology business.industry Magnetic resonance imaging Pattern recognition General Medicine Control subjects Correlation Nuclear magnetic resonance Partial inversion biology.animal Pattern recognition (psychology) Content (measure theory) medicine Artificial intelligence Tapir business Mathematics |
| Zdroj: | International Congress Series. 1265:113-123 |
| ISSN: | 0531-5131 |
| DOI: | 10.1016/j.ics.2004.02.168 |
| Popis: | We present two methods for the mapping of the T 1 and T 2 * relaxation times. A recently published sequence, T 1 mApping with Partial Inversion Recovery (TAPIR), is used for T 1 mapping in a cohort of patients suffering from hepatic encephalopathy (HE). TAPIR enables the fast and precise measurement of T 1 with whole brain coverage in approximately 5 min, which makes it a favourable tool for clinical applications. A clear correlation between HE severity and T 1 measured with TAPIR is demonstrated for several brain regions. Patients and control subjects could be classified solely based on their T 1 pattern by making use of unsupervised pattern recognition tools. In addition, a newly developed sequence termed QUanTitativE-EPI (QUTE-EPI) is presented for the fast and precise mapping of T 2 * without significant image distortions. The information provided by TAPIR and QUTE-EPI can be used to extract an absolute measure of water content in vivo by MRI. The procedure of H 2 O content mapping is described and results are presented. We demonstrate that in vivo water measurement is possible in clinically relevant measurement times with a statistical and systematic measurement error |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect