Description of parallel and sequential configurations for concurrent therapeutic plasma exchange and continuous kidney replacement therapy in adults

Autor: Li Choo Ng, Manish Kaushik, Ling Cao, Thinesh Lee Krishnamoorthy, Riece Koniman, Su Hooi Teo, Zhong Hong Liew, Han Khim Tan, Ghee Chee Phua, Duu-Wen Sewa, S.I.N:G.A.P.O.R.E Initiative, Amy Ee Lin Lim, Shin Yi Ng
Rok vydání: 2020
Předmět:
Zdroj: Journal of Clinical Apheresis. 36:211-218
ISSN: 1098-1101
0733-2459
Popis: Therapeutic plasma exchange (TPE) and continuous kidney replacement therapy (CKRT) are extracorporeal therapeutic procedures often implemented in management of patients. Critically ill patients may be afflicted with disease processes that require both TPE and CKRT. Performing TPE discontinuous with CKRT is technically easier, however, it disrupts CKRT and may compromise with CKRT efficiency or hemofilter life. Concurrent TPE with CKRT offers several advantages including simultaneous control of disease process and correction of electrolyte, fluid, and acid-base disturbances that may accompany TPE. Additionally, TPE may be performed by either centrifugation method or membrane plasma separation method. The technical specifications of these methods may influence the methodology of concurrent connections. This report describes and reviews two different approaches to circuit arrangements when establishing concurrent TPE and CKRT.
Databáze: OpenAIRE