Retraction Note: A deep learning model and machine learning methods for the classification of potential coronavirus treatments on a single human cell
| Autor: | Mohamed Loey, Nour Eldeen M. Khalifa, Gunasekaran Manogaran, Mohamed Hamed N. Taha |
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| Rok vydání: | 2021 |
| Předmět: |
Image domain
Materials science Treatment classification business.industry Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Deep learning Pooling Decision tree Bioengineering General Chemistry Human cell Condensed Matter Physics Machine learning computer.software_genre Atomic and Molecular Physics and Optics Support vector machine Modeling and Simulation General Materials Science Artificial intelligence business computer |
| Zdroj: | Journal of Nanoparticle Research. 23 |
| ISSN: | 1572-896X 1388-0764 |
| DOI: | 10.1007/s11051-021-05266-6 |
| Popis: | Coronavirus pandemic is burdening healthcare systems around the world to the full capacity they can accommodate. There is an overwhelming need to find a treatment for this virus as early as possible. Computer algorithms and deep learning can participate positively by finding a potential treatment for SARS-CoV-2. In this paper, a deep learning model and machine learning methods for the classification of potential coronavirus treatments on a single human cell will be presented. The dataset selected in this work is a subset of the publicly online datasets available on RxRx.ai. The objective of this research is to automatically classify a single human cell according to the treatment type and the treatment concentration level. A DCNN model and a methodology are proposed throughout this work. The methodical idea is to convert the numerical features from the original dataset to the image domain and then fed them up into a DCNN model. The proposed DCNN model consists of three convolutional layers, three ReLU layers, three pooling layers, and two fully connected layers. The experimental results show that the proposed DCNN model for treatment classification (32 classes) achieved 98.05% in testing accuracy if it is compared with classical machine learning such as support vector machine, decision tree, and ensemble. In treatment concentration level prediction, the classical machine learning (ensemble) algorithm achieved 98.5% in testing accuracy while the proposed DCNN model achieved 98.2%. The performance metrics strengthen the obtained results from the conducted experiments for the accuracy of treatment classification and treatment concentration level prediction. |
| Databáze: | OpenAIRE |
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