Antidiabetic and antioxidant effect of methanol extract of edible plant Talinum portulacifolium (Forssk) in Streptozotocin induced diabetic rats

Autor:	Subhash C. Mandal, Mohana Lakshmi Sabapathi, Nageswara Rao Thalapaneni, Faraz Raza Ansari
Rok vydání:	2011
Předmět:	medicine.medical_specialty Antioxidant Glycogen Chemistry Cholesterol medicine.medical_treatment Glutathione Malondialdehyde Streptozotocin Glibenclamide chemistry.chemical_compound Endocrinology Complementary and alternative medicine Internal medicine medicine Alkaline phosphatase medicine.drug
Zdroj:	Oriental Pharmacy and Experimental Medicine. 11:191-198
ISSN:	2211-1069 1598-2386
DOI:	10.1007/s13596-011-0026-2
Popis:	The aim of this study is to evaluate antidiabetic and antioxidant effects of methanol extract of Talinum portulacifolium (FORSSK) leaves (Portulacaceae) (METP) in streptozotocin induced diabetic rats. The acute and sub acute antihyperglycemic effect of two different doses (200 and 400 mg/kg,) of METP were investigated. Blood glucose level, serum insulin level, lipid profiles and biomarker enzymes were evaluated in normal and diabetic rats. Liver glycogen content, kidney and liver antioxidant enzymes were evaluated. Supplementation of METP by oral gavage significantly reduces the fasting blood glucose level. This supplementation significantly increases the glycogen level in the liver (32.33 ± 1.453 mg/gm) as compare to diabetic control group (5.66 ± 0.881 mg/gm) (p
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::5edd7beeb14562a92839baf2e4128525 https://doi.org/10.1007/s13596-011-0026-2 Zobrazit plný text záznamu Full text from SpringerLink