Impact of Bariatric Surgery on Endometrial Cancer Tumor Pathology
| Autor: | David A. Mahvi, Eric G. Sheu, Ali Ardestani, Olivia Foley, Ali Tavakkoli |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Nutrition and Dietetics Hysterectomy business.industry Endocrinology Diabetes and Metabolism medicine.medical_treatment Endometrial cancer Cancer 030209 endocrinology & metabolism medicine.disease Surgery Endometrial hyperplasia 03 medical and health sciences 0302 clinical medicine Weight loss Cohort medicine Adenocarcinoma 030211 gastroenterology & hepatology medicine.symptom Risk factor business |
| Zdroj: | Obesity Surgery. 31:2426-2433 |
| ISSN: | 1708-0428 0960-8923 |
| Popis: | Obesity is a well-established risk factor for endometrial cancer and is thought to adversely affect outcomes. The impact of significant and sustained weight loss as achieved by bariatric surgery for women with endometrial cancer is not well understood. We performed an institutional retrospective review of patients who underwent bariatric surgery and were diagnosed with premalignant or malignant uterine disease from 1989 to 2019 (n=171). We compared tumor characteristics and cancer-specific outcomes in patients diagnosed with uterine disease before (“PRE” group) or after (“POST” group) undergoing bariatric surgery and in a BMI- and age-matched cohort who did not undergo bariatric surgery. Of the 171 patients, 120 were in the PRE group and 51 in the POST group. The POST group was more likely to have adenocarcinoma (68.6 vs 45.0%, p=0.012) and more likely to have a minimally invasive hysterectomy (80.9 vs 46.2%, p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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