Dactylospongiaquinone, a new meroterpenoid from the Australian marine sponge Dactylospongia n. sp

Autor:	Aroon Jankam, John N. A. Hooper, Michael J. Somerville, Apichart Suksamrarn, Douglas J. Brecknell, Mary J. Garson
Rok vydání:	2007
Předmět:	biology Stereochemistry Metabolite Organic Chemistry Ring (chemistry) biology.organism_classification Biochemistry Cyclopropane Quinone chemistry.chemical_compound Sponge chemistry Drug Discovery Dactylospongia Two-dimensional nuclear magnetic resonance spectroscopy
Zdroj:	Tetrahedron. 63:1577-1582
ISSN:	0040-4020
DOI:	10.1016/j.tet.2006.12.006
Popis:	Chemical investigation of the sponge Dactylospongia n. sp. collected near Mooloolaba, S.E. Queensland, has led to the isolation of dactylospongiaquinone (7) together with the known quinones (2-5). The new metabolite 7 possesses a different carbon framework from the known dictyoceratidaquinone (9) and is suggested to possess a cis-fused ring junction by extensive NOESY studies combined with molecular modelling calculations. The relative stereochemistry of the previously described cyclospongiaquinone-1 (3) and dehydrocyclospongiaquinone-1 (4) is also assigned on the basis of NOESY analyses. Full NMR spectroscopic assignments are provided for all compounds. (c) 2006 Elsevier Ltd. All rights reserved.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::5eb74f9ebe95766f3fb87d107696a497 https://doi.org/10.1016/j.tet.2006.12.006 Zobrazit plný text záznamu Full Text from ScienceDirect