Metatypical Basal Cell Carcinoma: Histopathological Features in Aggressive Tumors

Autor: Lenine Garcia Brandão, Oscar Israel Jaramillo Calvas, Natália Martins Magacho de Andrade, André Bandiera de Oliveira Santos, Claudio Roberto Cernea
Rok vydání: 2013
Předmět:
Zdroj: Otolaryngology–Head and Neck Surgery. 149
ISSN: 1097-6817
0194-5998
DOI: 10.1177/0194599813496044a113
Popis: Objectives:The incidence and histological characteristics of metatypical basal cell carcinoma (MBCC) are divergent in the literature, especially in large dimension lesions. Retrospective studies suggest that this neoplasm represents from 1.2% to 2.7% of all BCCs, with a particular behavior that is prone to metastasis. The purpose of this study is to compare the demographics and histopathological features of cervicofacial MBCC with other BCCs treated by head and neck surgery.Methods:Data from 354 basal cell carcinomas were reviewed (1994-2012). Sex, age, histological subtype, localization, size, perineural and angiolymphatic invasions were analyzed, comparing MBCC with other basal cell carcinoma subtypes.Results:MBCC was found in 35 cases (10.77%), either as principal or associated subtype. Average age of MBCC was 64.8 ± 12.8, and 65.1 ± 14.2 years in the other group (P = 0.89). There was no statistical difference in the items sex and angiolymphathic invasion. Zone H tumors were in 75.6% of MBCC and 89.7% ...
Databáze: OpenAIRE
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