General and Highly Efficient Syntheses ofm-Fluoro Arenes Using Potassium Fluoride-Exchange Method

Autor:	Yasuo Yoshida, Naoto Yazawa, Yoshikazu Kimura, Osamu Furusawa, Hiroshi Suzuki
Rok vydání:	1990
Předmět:	chemistry.chemical_compound Trifluoromethyl chemistry Tetraphenylphosphonium bromide Aryl Nitro Organic chemistry General Chemistry Potassium fluoride Stoichiometry Catalysis
Zdroj:	Bulletin of the Chemical Society of Japan. 63:2010-2017
ISSN:	1348-0634 0009-2673
Popis:	Tetraphenylphosphonium bromide was found to be a suitable catalyst for the reaction of m-nitroaryl derivatives carrying cyano, nitro, chlorocarbonyl, trifluoromethyl, and chlorosulfonyl groups with potassium fluoride in the presence of a stoichiometric amount of phthaloyl dichloride, giving the corresponding m-fluoro aromatic derivatives in good yields. The catalyst was also found to be efficient for the fluorodesulfonylation of m-(fluorosulfonyl)aryl derivatives to afford m-fluoro arenes by the use of a reaction-distillation technique.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::5e9a45c54bccbacb57a0379dcea314c1 https://doi.org/10.1246/bcsj.63.2010 Zobrazit plný text záznamu