Overview on the efficacy and safety of gadobutrol: an MRI contrast agent for the CNS, body and vessels

Autor: Sara S. K. Koenig, Juan E. Gutierrez, Josy Breuer
Rok vydání: 2012
Předmět:
Zdroj: Imaging in Medicine. 4:25-40
ISSN: 1755-5205
1755-5191
DOI: 10.2217/iim.11.70
Popis: Contrast-enhanced MRI has become a mainstay of clinical imaging with unlimited applications. However, a limitation of conventional contrast agents in MRI is the insufficient signal-to-noise ratios due to relaxivity. Gadobutrol (1.0 mmol/ml), an extracellular macrocyclic contrast agent of high stability, is indicated for contrast-enhanced MRI of adults, adolescents and children 2 years of age and older. Gadobutrol offers increased T1 relaxivity, which improves MR image quality and clinical use of the technique.
Databáze: OpenAIRE