THE EFFECT OF IODINE AND IODOTHYRIN ON THE LARVÆ OF SALAMANDERS. III. THE RÔLE OF THE IODINE IN THE SPECIFIC ACTION OF THE THYROID HORMONE AS TESTED IN THE METAMORPHOSIS OF THE AXOLOTL LARVÆ
| Autor: | E. Uhlenhuth |
|---|---|
| Rok vydání: | 1922 |
| Předmět: |
Larva
medicine.medical_specialty biology media_common.quotation_subject Thyroid chemistry.chemical_element Iodothyrin biology.organism_classification Iodine Endocrinology medicine.anatomical_structure chemistry Axolotl biology.animal Internal medicine medicine Salamander Metamorphosis General Agricultural and Biological Sciences media_common Hormone |
| Zdroj: | The Biological Bulletin. 42:143-152 |
| ISSN: | 1939-8697 0006-3185 |
| DOI: | 10.2307/1536577 |
| Popis: | 1. Iodothyrin and inorganic iodine, in known quantities, were administered to so-called axolotl larvae of the salamander Ambystoma tigrinum.2. A dosis of iodothyrin containing only 0.03 mgm. iodine per 1,000 c.c. of water caused metamorphosis 13 days after its first administration.3. A dosis of inorganic iodine 33 to 86 times larger and feeding still larger doses directly per mouth did not cause metamorphosis.4. The amphibian metamorphosis is truly the expression of the thyroid activity and not the result of the effect of inorganic iodine.5. Inorganic iodine as such is not the active principle of the thyroid hormone. |
| Databáze: | OpenAIRE |
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