Significance of various adrenoreceptors for brain resistance to total ischemia
| Autor: | V. I. Kulinskii, T. N. Medvedeva |
|---|---|
| Rok vydání: | 1996 |
| Předmět: |
medicine.medical_specialty
business.industry Rauwolscine General Medicine Propranolol medicine.disease General Biochemistry Genetics and Molecular Biology Clonidine Brain ischemia chemistry.chemical_compound Epinephrine Endocrinology chemistry Internal medicine Isoprenaline medicine cardiovascular diseases Methyldopa business Phenylephrine medicine.drug |
| Zdroj: | Bulletin of Experimental Biology and Medicine. 121:142-144 |
| ISSN: | 1573-8221 0007-4888 |
| DOI: | 10.1007/bf02446619 |
| Popis: | In contrast to the β-agonist isoprenaline and the α1-agonist phenylephrine, the α2-agonists clonidine, guanobenz, and methyldopa are highly effective against total brain ischemia. Epinephrine in itself is inactive but displays protective activity against the background of the β-antagonist propranolol. The α2-antagonist rauwolscine, but not α1-antagonists, abolish the protective effect of clonidine. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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