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The purpose of this article is to explore the effectiveness of case-based learning (CBL) as a teaching method, which was applied in the teaching of the kidney diseases in internal medicine of traditional Chinese medicine (TCM). The method was as follows: There were sixty undergraduates selected as the CBL experimental group in Soochow University, and the CBL was adopted to the study of the kidney disease of traditional Chinese medicine. At the same time the Lecture Based Learning (LBL) method was applied in another class, which was took as the control group. At the end of this semester, using the way of questionnaires and score statistics of theoretical knowledge, we evaluated the teaching effect which based on a qualitative approach and the analysis of the medical record. The content of the questionnaire involves whether or not to stimulate the learning interest, the enthusiasm of study, the ability of self-study, the comprehensive analysis ability, the ability of independent thinking, and promote the interaction relation between teachers and students. The result showed that there was significant difference between the CBL group and the LBL group on the basis of theoretical examination results (P |