Congenital unilateral absence of a pulmonary artery
| Autor: | S. Gilbert Blount, Peter E. Pool, John H.K. Vogel |
|---|---|
| Rok vydání: | 1962 |
| Předmět: |
medicine.medical_specialty
Lung business.industry Incidence (epidemiology) Left pulmonary artery medicine.disease Pulmonary hypertension Shunt (medical) Surgery Lesion medicine.anatomical_structure medicine.artery Internal medicine Pulmonary artery medicine Cardiology Differential diagnosis medicine.symptom Cardiology and Cardiovascular Medicine business |
| Zdroj: | The American Journal of Cardiology. 10:706-732 |
| ISSN: | 0002-9149 |
| DOI: | 10.1016/0002-9149(62)90248-5 |
| Popis: | This review and supporting experiments in which the left pulmonary artery was ligated on the first day of life, have clearly implicated an increased pulmonary blood flow from the time of birth as an important factor in the genesis of pulmonary hypertension. Ninety-eight cases of unilateral absence of a pulmonary artery, including four new cases, have been collected from the world's literature and are reviewed in this paper. This lesion is frequently undiagnosed and may be more common than is generally appreciated as shown by the marked increase in case reports in the past ten years. The blood supply to the affected lung has been explained on an embryologie basis, and two distinct embryologic faults have been implicated. The incidence of pulmonary hypertension in the isolated cases was 19 per cent, and when combined with a cardiovascular shunt the incidence was 88 per cent. In view of the high incidence of pulmonary hypertension when UAPA is associated with a cardiovascular shunt, it is important to recognize these patients at an early age and correct the associated shunt to prevent or reverse pulmonary hypertension, if possible. It is evident that this lesion must be considered in the differential diagnosis of pulmonary hypertension and cyanotic congenital heart disease. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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