Experimental Bacteremic Vascular Graft Infection with Staphylococcus aureus. Comparative Colonization of Two Graft Materials and Prophylaxis of Late Infection

Autor: Olivier Goëau-Brissonnière, Jean-Claude Péchere, Catherine Leport, Claude Lebrault
Rok vydání: 1990
Předmět:
Zdroj: Pathogenesis of Wound and Biomaterial-Associated Infections ISBN: 9783540195962
DOI: 10.1007/978-1-4471-3454-1_57
Popis: In a dog model reproducing colonization of a vascular graft through an experimental bacteremia caused by Staphylococcus aureus, Dacron grafts were more colonized than ePTFE grafts for durations of graft function of 2 hours up to 2 months, while at 6 months the inverse trend was observed, both material being still more susceptible than normal aortas. A single injection of ceftriaxone 90 minutes before the bacteremic challenge completely prevented late graft infection.
Databáze: OpenAIRE